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Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes

BACKGROUND: Hepatotoxicity is a form of liver injury caused by exposure to stressors. Genomic-based approaches have been used to detect changes in transcription in response to hepatotoxicants. However, there are no straightforward ways of using co-expressed genes anchored to a phenotype or constrain...

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Detalles Bibliográficos
Autores principales: Chou, Jeff W, Bushel, Pierre R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706894/
https://www.ncbi.nlm.nih.gov/pubmed/19538742
http://dx.doi.org/10.1186/1471-2164-10-272