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STAT3 deletion sensitizes cells to oxidative stress

The transcription factor STAT1 plays a role in promoting apoptotic cell death, whereas the related STAT3 transcription factor protects cardiac myocytes from ischemia/reperfusion (I/R) injury or oxidative stress. Cytokines belonging to the IL-6 family activate the JAK-STAT3 pathway, but also activate...

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Detalles Bibliográficos
Autores principales: Barry, Seán P., Townsend, Paul A., McCormick, James, Knight, Richard A., Scarabelli, Tiziano M., Latchman, David S., Stephanou, Anastasis
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706948/
https://www.ncbi.nlm.nih.gov/pubmed/19450559
http://dx.doi.org/10.1016/j.bbrc.2009.05.051