Phospho-Ablated Id2 Is Growth Suppressive and Pro-Apoptotic in Proliferating Myoblasts

Inhibitor of differentiation protein-2 (Id2) is a dominant negative helix-loop-helix (HLH) protein, and a positive regulator of proliferation, in various cells. The N-terminal region of Id2 contains a consensus cdk2 phosphorylation sequence SPVR, which may be involved with the induction of apoptosis...

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Detalles Bibliográficos
Autores principales: Butler, David C., Haramizu, Satoshi, Williamson, David L., Alway, Stephen E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706990/
https://www.ncbi.nlm.nih.gov/pubmed/19609365
http://dx.doi.org/10.1371/journal.pone.0006302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706990/
https://www.ncbi.nlm.nih.gov/pubmed/19609365
http://dx.doi.org/10.1371/journal.pone.0006302

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