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Phospho-Ablated Id2 Is Growth Suppressive and Pro-Apoptotic in Proliferating Myoblasts
Inhibitor of differentiation protein-2 (Id2) is a dominant negative helix-loop-helix (HLH) protein, and a positive regulator of proliferation, in various cells. The N-terminal region of Id2 contains a consensus cdk2 phosphorylation sequence SPVR, which may be involved with the induction of apoptosis...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706990/ https://www.ncbi.nlm.nih.gov/pubmed/19609365 http://dx.doi.org/10.1371/journal.pone.0006302 |