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Overexpression of the rhamnose catabolism regulatory protein, RhaR: a novel mechanism for metronidazole resistance in Bacteroides thetaiotaomicron

OBJECTIVES: The aim of the investigation was to use in vitro transposon mutagenesis to generate metronidazole resistance in the obligately anaerobic pathogenic bacterium Bacteroides thetaiotaomicron, and to identify the genes involved to enable investigation of potential mechanisms for the generatio...

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Detalles Bibliográficos
Autores principales: Patel, Ekta H., Paul, Lynthia V., Casanueva, Ana I., Patrick, Sheila, Abratt, Valerie R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707267/
https://www.ncbi.nlm.nih.gov/pubmed/19525515
http://dx.doi.org/10.1093/jac/dkp203