Accounting for uncertainty when assessing association between copy number and disease: a latent class model

BACKGROUND: Copy number variations (CNVs) may play an important role in disease risk by altering dosage of genes and other regulatory elements, which may have functional and, ultimately, phenotypic consequences. Therefore, determining whether a CNV is associated or not with a given disease might be...

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Detalles Bibliográficos
Autores principales: González, Juan R, Subirana, Isaac, Escaramís, Geòrgia, Peraza, Solymar, Cáceres, Alejandro, Estivill, Xavier, Armengol, Lluís
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707368/
https://www.ncbi.nlm.nih.gov/pubmed/19500389
http://dx.doi.org/10.1186/1471-2105-10-172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707368/
https://www.ncbi.nlm.nih.gov/pubmed/19500389
http://dx.doi.org/10.1186/1471-2105-10-172

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