Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells

Self-renewing cell populations such as hematopoietic stem cells and memory B and T lymphocytes might be regulated by shared signaling pathways1. Wnt/β-catenin is an evolutionarily conserved pathway that promotes hematopoietic stem cell self-renewal and multipotency by limiting stem cell proliferatio...

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Detalles Bibliográficos
Autores principales: Gattinoni, Luca, Zhong, Xiao-Song, Palmer, Douglas C, Ji, Yun, Hinrichs, Christian S, Yu, Zhiya, Wrzesinski, Claudia, Boni, Andrea, Cassard, Lydie, Church, Lindsay, Paulos, Chrystal M, Muranski, Pawel, Restifo, Nicholas P
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707501/
https://www.ncbi.nlm.nih.gov/pubmed/19525962
http://dx.doi.org/10.1038/nm.1982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707501/
https://www.ncbi.nlm.nih.gov/pubmed/19525962
http://dx.doi.org/10.1038/nm.1982

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