Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness

Monitoring Trypanosoma spread using real-time imaging in vivo provides a fast method to evaluate parasite distribution especially in immunoprivileged locations. Here, we generated monomorphic and pleomorphic recombinant Trypanosoma brucei expressing the Renilla luciferase. In vitro luciferase activi...

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Detalles Bibliográficos
Autores principales: Claes, Filip, Vodnala, Suman K., van Reet, Nick, Boucher, Nathalie, Lunden-Miguel, Hilda, Baltz, Theo, Goddeeris, Bruno Maria, Büscher, Philippe, Rottenberg, Martin E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707598/
https://www.ncbi.nlm.nih.gov/pubmed/19621071
http://dx.doi.org/10.1371/journal.pntd.0000486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707598/
https://www.ncbi.nlm.nih.gov/pubmed/19621071
http://dx.doi.org/10.1371/journal.pntd.0000486

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