Protease Activated Receptor Signaling Is Required for African Trypanosome Traversal of Human Brain Microvascular Endothelial Cells

BACKGROUND: Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we recently reported that the parasites cross the BBB by generating calcium activation signals in HBMECs through the activity of parasite...

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Detalles Bibliográficos
Autores principales: Grab, Dennis J., Garcia-Garcia, Jose C., Nikolskaia, Olga V., Kim, Yuri V., Brown, Amanda, Pardo, Carlos A., Zhang, Yongqing, Becker, Kevin G., Wilson, Brenda A., de A. Lima, Ana Paula C., Scharfstein, Julio, Dumler, J. Stephen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707606/
https://www.ncbi.nlm.nih.gov/pubmed/19621073
http://dx.doi.org/10.1371/journal.pntd.0000479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707606/
https://www.ncbi.nlm.nih.gov/pubmed/19621073
http://dx.doi.org/10.1371/journal.pntd.0000479

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