Conformationally Constrained Analogues of Diacylglycerol (DAG). 31. Modulation of the Biological Properties of Diacylgycerol Lactones (DAG-lactones) Containing Rigid-Rod Acyl Groups Separated from the Core Lactone by Spacer Units of Different Lengths

[Image: see text] Diacylglycerol lactones built with a rigid 4-[(methylphenyl)ethynyl]phenyl rod that is separated from the exocyclic acylcarbonyl of the DAG-lactone core by a spacer unit of variable length were synthesized and studied. Binding affinities for a panel of classical and novel PKC isozy...

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Detalles Bibliográficos
Autores principales: Comin, Maria J., Czifra, Gabriella, Kedei, Noemi, Telek, Andrea, Lewin, Nancy E., Kolusheva, Sofiya, Velasquez, Julia F., Kobylarz, Ryan, Jelinek, Raz, Blumberg, Peter M., Marquez, Victor E.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708097/
https://www.ncbi.nlm.nih.gov/pubmed/19379015
http://dx.doi.org/10.1021/jm900186m

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708097/
https://www.ncbi.nlm.nih.gov/pubmed/19379015
http://dx.doi.org/10.1021/jm900186m

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