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Oral vaccination with a recombinant Salmonella vaccine vector provokes systemic HIV-1 subtype C Gag-specific CD4+ Th1 and Th2 cell immune responses in mice

BACKGROUND: Recombinant Salmonella vaccine vectors may potentially be used to induce specific CD4+ T cell responses against foreign viral antigens. Such immune responses are required features of vaccines against pathogens such as human immunodeficiency virus type 1 (HIV-1). The aim of this study was...

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Detalles Bibliográficos
Autores principales: Chin'ombe, Nyasha, Bourn, William R, Williamson, Anna-Lise, Shephard, Enid G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708135/
https://www.ncbi.nlm.nih.gov/pubmed/19555490
http://dx.doi.org/10.1186/1743-422X-6-87