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Cytochrome-P450 enzymes and autoimmunity: expansion of the relationship and introduction of free radicals as the link
The Cytochrome-P-450 enzymes (CYP) are among the most important xenobiotic-metabolizing enzymes, which produce reactive oxygen species (ROS) as the result of metabolizing xenobiotics. ROS are believed to play important roles in the pathophysiology of autoimmune diseases. ROS can alter the structure...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708150/ https://www.ncbi.nlm.nih.gov/pubmed/19555503 http://dx.doi.org/10.1186/1740-2557-6-4 |