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Improved Methodology for Assessment of mRNA Levels in Blood of Patients with FMR1 Related Disorders

BACKGROUND: Elevated levels of FMR1 mRNA in blood have been implicated in RNA toxicity associated with a number of clinical conditions. Due to the extensive inter-sample variation in the time lapse between the blood collection and RNA extraction in clinical practice, the resulting variation in mRNA...

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Detalles Bibliográficos
Autores principales: Godler, David E, Loesch, Danuta Z, Huggins, Richard, Gordon, Lavinia, Slater, Howard R, Gehling, Freya, Burgess, Trent, Choo, KH Andy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708186/
https://www.ncbi.nlm.nih.gov/pubmed/19505339
http://dx.doi.org/10.1186/1472-6890-9-5