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Interim data monitoring to enroll higher-risk participants in HIV prevention trials

BACKGROUND: Lower-than-expected incidence of HIV undermines sample size calculations and compromises the power of a HIV prevention trial. We evaluated the effectiveness of interim monitoring of HIV infection rates and on-going modification of recruitment strategies to enroll women at higher risk of...

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Detalles Bibliográficos
Autores principales: Halpern, Vera, Obunge, Orikomaba, Ogunsola, Folasade, Otusanya, Sakiru, Umo-Otong, John, Wang, Chin-Hua, Mehta, Neha
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708194/
https://www.ncbi.nlm.nih.gov/pubmed/19549331
http://dx.doi.org/10.1186/1471-2288-9-44