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Aneuploidy and Improved Growth Are Coincident but Not Causal in a Yeast Cancer Model

Cancer cells have acquired mutations that alter their growth. Aneuploidy that typify cancer cells are often assumed to contribute to the abnormal growth characteristics. Here we test the idea of a link between aneuploidy and mutations allowing improved growth, using Saccharomyces cerevisiae containi...

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Detalles Bibliográficos
Autores principales: Li, Xin Chenglin, Schimenti, John C., Tye, Bik K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708349/
https://www.ncbi.nlm.nih.gov/pubmed/19636358
http://dx.doi.org/10.1371/journal.pbio.1000161