Separate Elements within a Single IQ-like Motif in Adenylyl Cyclase Type 8 Impart Ca(2+)/Calmodulin Binding and Autoinhibition

The ubiquitous Ca(2+)-sensing protein calmodulin (CaM) fulfills its numerous signaling functions through a wide range of modular binding and activation mechanisms. By activating adenylyl cyclases (ACs) 1 and 8, Ca(2+) acting via calmodulin impacts on the signaling of the other major cellular second...

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Detalles Bibliográficos
Autores principales: MacDougall, David A., Wachten, Sebastian, Ciruela, Antonio, Sinz, Andrea, Cooper, Dermot M. F.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708854/
https://www.ncbi.nlm.nih.gov/pubmed/19305019
http://dx.doi.org/10.1074/jbc.M809585200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708854/
https://www.ncbi.nlm.nih.gov/pubmed/19305019
http://dx.doi.org/10.1074/jbc.M809585200

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