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Separate Elements within a Single IQ-like Motif in Adenylyl Cyclase Type 8 Impart Ca(2+)/Calmodulin Binding and Autoinhibition
The ubiquitous Ca(2+)-sensing protein calmodulin (CaM) fulfills its numerous signaling functions through a wide range of modular binding and activation mechanisms. By activating adenylyl cyclases (ACs) 1 and 8, Ca(2+) acting via calmodulin impacts on the signaling of the other major cellular second...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708854/ https://www.ncbi.nlm.nih.gov/pubmed/19305019 http://dx.doi.org/10.1074/jbc.M809585200 |