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Dysregulation of Human β-Defensin-2 Protein in Inflammatory Bowel Disease
BACKGROUND: Human β-defensin-2 (HBD2) is an antimicrobial peptide implicated in the pathogenesis of inflammatory bowel disease (IBD). Low copy number and concomitant low mRNA expression of the HBD2 gene have been implicated in susceptibility to colonic Crohn's Disease (CD). We investigated the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708916/ https://www.ncbi.nlm.nih.gov/pubmed/19617917 http://dx.doi.org/10.1371/journal.pone.0006285 |