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Dysregulation of Human β-Defensin-2 Protein in Inflammatory Bowel Disease

BACKGROUND: Human β-defensin-2 (HBD2) is an antimicrobial peptide implicated in the pathogenesis of inflammatory bowel disease (IBD). Low copy number and concomitant low mRNA expression of the HBD2 gene have been implicated in susceptibility to colonic Crohn's Disease (CD). We investigated the...

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Detalles Bibliográficos
Autores principales:	Aldhous, Marian C., Noble, Colin L., Satsangi, Jack
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708916/ https://www.ncbi.nlm.nih.gov/pubmed/19617917 http://dx.doi.org/10.1371/journal.pone.0006285

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