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Anaplastic lymphoma kinase: signalling in development and disease
RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and differentiation. In addition, RTKs reveal oncogenic potential when their kinase activities are constitutively enhanced by point mutation, amplification or rearrangement of the corresponding genes. The ALK (anaplastic...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708929/ https://www.ncbi.nlm.nih.gov/pubmed/19459784 http://dx.doi.org/10.1042/BJ20090387 |