Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein kinase C) family kinases such as Akt (protein kinase B), S6K (p70 ribosomal S6 kinase) and SGK (serum and glucocorticoid protein kinase). mTORC1 (...

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Detalles Bibliográficos
Autores principales: García-Martínez, Juan M., Moran, Jennifer, Clarke, Rosemary G., Gray, Alex, Cosulich, Sabina C., Chresta, Christine M., Alessi, Dario R.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708931/
https://www.ncbi.nlm.nih.gov/pubmed/19402821
http://dx.doi.org/10.1042/BJ20090489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708931/
https://www.ncbi.nlm.nih.gov/pubmed/19402821
http://dx.doi.org/10.1042/BJ20090489

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