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NEMO oligomerization and its ubiquitin-binding properties

The IKK [IκB (inhibitory κB) kinase] complex is a key regulatory component of NF-κB (nuclear factor κB) activation and is responsible for mediating the degradation of IκB, thereby allowing nuclear translocation of NF-κB and transcription of target genes. NEMO (NF-κB essential modulator), the regulat...

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Detalles Bibliográficos
Autores principales: Ivins, Frank J., Montgomery, Mark G., Smith, Susan J. M., Morris-Davies, Aylin C., Taylor, Ian A., Rittinger, Katrin
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708934/
https://www.ncbi.nlm.nih.gov/pubmed/19422324
http://dx.doi.org/10.1042/BJ20090427