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NEMO oligomerization and its ubiquitin-binding properties
The IKK [IκB (inhibitory κB) kinase] complex is a key regulatory component of NF-κB (nuclear factor κB) activation and is responsible for mediating the degradation of IκB, thereby allowing nuclear translocation of NF-κB and transcription of target genes. NEMO (NF-κB essential modulator), the regulat...
Autores principales: | Ivins, Frank J., Montgomery, Mark G., Smith, Susan J. M., Morris-Davies, Aylin C., Taylor, Ian A., Rittinger, Katrin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708934/ https://www.ncbi.nlm.nih.gov/pubmed/19422324 http://dx.doi.org/10.1042/BJ20090427 |
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