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(124)I-L19-SIP for immuno-PET imaging of tumour vasculature and guidance of (131)I-L19-SIP radioimmunotherapy

PURPOSE: The human monoclonal antibody (MAb) fragment L19-SIP is directed against extra domain B (ED-B) of fibronectin, a marker of tumour angiogenesis. A clinical radioimmunotherapy (RIT) trial with (131)I-L19-SIP was recently started. In the present study, after GMP production of (124)I and effici...

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Detalles Bibliográficos
Autores principales: Tijink, Bernard M., Perk, Lars R., Budde, Marianne, Stigter-van Walsum, Marijke, Visser, Gerard W. M., Kloet, Reina W., Dinkelborg, Ludger M., Leemans, C. René, Neri, Dario, van Dongen, Guus A. M. S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709218/
https://www.ncbi.nlm.nih.gov/pubmed/19259661
http://dx.doi.org/10.1007/s00259-009-1096-y