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Endosomal Adaptor Proteins APPL1 and APPL2 Are Novel Activators of β-Catenin/TCF-mediated Transcription

Canonical Wnt signaling regulates many aspects of cellular physiology and tissue homeostasis during development and in adult organisms. In molecular terms, stimulation by Wnt ligands leads to the stabilization of β-catenin, its translocation to the nucleus, and stimulation of TCF (T-cell factor)-dep...

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Detalles Bibliográficos
Autores principales: Rashid, Sajid, Pilecka, Iwona, Torun, Anna, Olchowik, Marta, Bielinska, Beata, Miaczynska, Marta
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709337/
https://www.ncbi.nlm.nih.gov/pubmed/19433865
http://dx.doi.org/10.1074/jbc.M109.007237