Hyperactivation of DNA-PK by Double-Strand Break Mimicking Molecules Disorganizes DNA Damage Response

Cellular response to DNA damage involves the coordinated activation of cell cycle checkpoints and DNA repair. The early steps of DNA damage recognition and signaling in mammalian cells are not yet fully understood. To investigate the regulation of the DNA damage response (DDR), we designed short and...

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Detalles Bibliográficos
Autores principales: Quanz, Maria, Chassoux, Danielle, Berthault, Nathalie, Agrario, Céline, Sun, Jian-Sheng, Dutreix, Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709433/
https://www.ncbi.nlm.nih.gov/pubmed/19621083
http://dx.doi.org/10.1371/journal.pone.0006298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709433/
https://www.ncbi.nlm.nih.gov/pubmed/19621083
http://dx.doi.org/10.1371/journal.pone.0006298

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