Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon

11q13 amplification is a late-stage event in several cancers that is often associated with poor prognosis. Among 11q13-amplified genes, the actin assembly protein cortactin/CTTN is considered a likely candidate for direct involvement in tumor progression, because of its cell motility-enhancing funct...

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Detalles Bibliográficos
Autores principales: Clark, Emily S., Brown, Brandee, Whigham, Amy S., Kochaishvili, Avtandyl, Yarbrough, Wendell G., Weaver, Alissa M.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709457/
https://www.ncbi.nlm.nih.gov/pubmed/18931703
http://dx.doi.org/10.1038/onc.2008.389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709457/
https://www.ncbi.nlm.nih.gov/pubmed/18931703
http://dx.doi.org/10.1038/onc.2008.389

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