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Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon
11q13 amplification is a late-stage event in several cancers that is often associated with poor prognosis. Among 11q13-amplified genes, the actin assembly protein cortactin/CTTN is considered a likely candidate for direct involvement in tumor progression, because of its cell motility-enhancing funct...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709457/ https://www.ncbi.nlm.nih.gov/pubmed/18931703 http://dx.doi.org/10.1038/onc.2008.389 |