Two- and Three-Dimensional Quantitative Structure-Activity Relationships Studies on a Series of Liver X Receptor Ligands

Liver X receptor (LXR) is an attractive drug target for the development of novel therapeutic agents for the treatment of dyslipidaemia and cholestasis. In the present work, comparative molecular field analysis (CoMFA) and hologram quantitative structure-activity relationship (HQSAR) studies were con...

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Detalles Bibliográficos
Autores principales: Honório, Káthia M, Salum, Lívia B, Garratt, Richard C, Polikarpov, Igor, Andricopulo, Adriano D
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709468/
https://www.ncbi.nlm.nih.gov/pubmed/19696872
http://dx.doi.org/10.2174/1874104500802010087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709468/
https://www.ncbi.nlm.nih.gov/pubmed/19696872
http://dx.doi.org/10.2174/1874104500802010087

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