Oligonucleotides suppress PKB/Akt and act as superinductors of apoptosis in human keratinocytes

DNA oligonucleotides (ODN) applied to an organism are known to modulate the innate and adaptive immune system. Previous studies showed that a CpG-containing ODN (CpG-1-PTO) and interestingly, also a non-CpG-containing ODN (nCpG-5-PTO) suppress inflammatory markers in skin. In the present study it wa...

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Detalles Bibliográficos
Autores principales: Kippenberger, Stefan, Müller, Jutta, Schultz, Maike, Dorn, Annette, Bock, Andreas, Aygün, Hüseyin, Thaçi, Diamant, Hofmann, Matthias, Kaufmann, Roland, Bernd, August
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709556/
https://www.ncbi.nlm.nih.gov/pubmed/19386618
http://dx.doi.org/10.1093/nar/gkp252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709556/
https://www.ncbi.nlm.nih.gov/pubmed/19386618
http://dx.doi.org/10.1093/nar/gkp252

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