Both helix topology and counterion distribution contribute to the more effective charge screening in dsRNA compared with dsDNA

The recent discovery of the RNA interference mechanism emphasizes the biological importance of short, isolated, double-stranded (ds) RNA helices and calls for a complete understanding of the biophysical properties of dsRNA. However, most previous studies of the electrostatics of nucleic acid duplexe...

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Detalles Bibliográficos
Autores principales: Pabit, Suzette A., Qiu, Xiangyun, Lamb, Jessica S., Li, Li, Meisburger, Steve P., Pollack, Lois
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709557/
https://www.ncbi.nlm.nih.gov/pubmed/19395592
http://dx.doi.org/10.1093/nar/gkp257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709557/
https://www.ncbi.nlm.nih.gov/pubmed/19395592
http://dx.doi.org/10.1093/nar/gkp257

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