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IHF-binding sites inhibit DNA loop formation and transcription initiation

Transcriptional activation of enhancer and σ(54)-dependent promoters requires efficient interactions between enhancer-binding proteins (EBP) and promoter bound σ(54)-RNA polymerase (Eσ(54)) achieved by DNA looping, which is usually facilitated by the integration host factor (IHF). Since the lengths...

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Detalles Bibliográficos
Autores principales: Huo, Yi-Xin, Zhang, Yuan-Tao, Xiao, Yan, Zhang, Xiaodong, Buck, Martin, Kolb, Annie, Wang, Yi-Ping
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709558/
https://www.ncbi.nlm.nih.gov/pubmed/19395594
http://dx.doi.org/10.1093/nar/gkp258