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High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers

Many genome-wide assays involve the generation of a subset (or representation) of the genome following restriction enzyme digestion. The use of enzymes sensitive to cytosine methylation allows high-throughput analysis of this epigenetic regulatory process. We show that the use of a dual-adapter appr...

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Detalles Bibliográficos
Autores principales: Oda, Mayumi, Glass, Jacob L., Thompson, Reid F., Mo, Yongkai, Olivier, Emmanuel N., Figueroa, Maria E., Selzer, Rebecca R., Richmond, Todd A., Zhang, Xinmin, Dannenberg, Luke, Green, Roland D., Melnick, Ari, Hatchwell, Eli, Bouhassira, Eric E., Verma, Amit, Suzuki, Masako, Greally, John M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709560/
https://www.ncbi.nlm.nih.gov/pubmed/19386619
http://dx.doi.org/10.1093/nar/gkp260