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High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers
Many genome-wide assays involve the generation of a subset (or representation) of the genome following restriction enzyme digestion. The use of enzymes sensitive to cytosine methylation allows high-throughput analysis of this epigenetic regulatory process. We show that the use of a dual-adapter appr...
Autores principales: | Oda, Mayumi, Glass, Jacob L., Thompson, Reid F., Mo, Yongkai, Olivier, Emmanuel N., Figueroa, Maria E., Selzer, Rebecca R., Richmond, Todd A., Zhang, Xinmin, Dannenberg, Luke, Green, Roland D., Melnick, Ari, Hatchwell, Eli, Bouhassira, Eric E., Verma, Amit, Suzuki, Masako, Greally, John M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709560/ https://www.ncbi.nlm.nih.gov/pubmed/19386619 http://dx.doi.org/10.1093/nar/gkp260 |
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