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Folding of the cocaine aptamer studied by EPR and fluorescence spectroscopies using the bifunctional spectroscopic probe Ç

The cocaine aptamer is a DNA molecule that binds cocaine at the junction of three helices. The bifunctional spectroscopic probe Ç was incorporated independently into three different positions of the aptamer and changes in structure and dynamics upon addition of the cocaine ligand were studied. Nucle...

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Detalles Bibliográficos
Autores principales: Cekan, Pavol, Jonsson, Elvar Örn, Sigurdsson, Snorri Th.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709570/
https://www.ncbi.nlm.nih.gov/pubmed/19406921
http://dx.doi.org/10.1093/nar/gkp277