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One RNA aptamer sequence, two structures: a collaborating pair that inhibits AMPA receptors
RNA is ideally suited for in vitro evolution experiments, because a single RNA molecule possesses both genotypic (replicable sequence) and phenotypic (selectable shape) properties. Using systematic evolution of ligands by exponential enrichment (SELEX), we found a single 58-nt aptamer sequence that...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709572/ https://www.ncbi.nlm.nih.gov/pubmed/19417060 http://dx.doi.org/10.1093/nar/gkp284 |