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One RNA aptamer sequence, two structures: a collaborating pair that inhibits AMPA receptors

RNA is ideally suited for in vitro evolution experiments, because a single RNA molecule possesses both genotypic (replicable sequence) and phenotypic (selectable shape) properties. Using systematic evolution of ligands by exponential enrichment (SELEX), we found a single 58-nt aptamer sequence that...

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Detalles Bibliográficos
Autores principales:	Huang, Zhen, Pei, Weimin, Han, Yan, Jayaseelan, Sabarinath, Shekhtman, Alexander, Shi, Hua, Niu, Li
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709572/ https://www.ncbi.nlm.nih.gov/pubmed/19417060 http://dx.doi.org/10.1093/nar/gkp284

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