Structural insights into CUG repeats containing the ‘stretched U–U wobble’: implications for myotonic dystrophy

Tracks containing CUG repeats are abundant in human gene transcripts. Their biological role includes modulation of pre-mRNA splicing, mRNA transport and regulation of translation. Expanded forms of CUG runs are associated with pathogenesis of several neurodegenerative diseases, including myotonic dy...

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Detalles Bibliográficos
Autores principales: Kiliszek, Agnieszka, Kierzek, Ryszard, Krzyzosiak, Wlodzimierz J., Rypniewski, Wojciech
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709583/
https://www.ncbi.nlm.nih.gov/pubmed/19433512
http://dx.doi.org/10.1093/nar/gkp350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709583/
https://www.ncbi.nlm.nih.gov/pubmed/19433512
http://dx.doi.org/10.1093/nar/gkp350

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