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Localization of CD26/DPPIV in nucleus and its nuclear translocation enhanced by anti-CD26 monoclonal antibody with anti-tumor effect

BACKGROUND: CD26 is a type II, cell surface glycoprotein known as dipeptidyl peptidase (DPP) IV. Previous studies have revealed CD26 expression in T cell leukemia/lymphoma and malignant mesothelioma, and an inhibitory effect of anti-CD26 monoclonal antibody (mAb) against the growth of CD26+ cancer c...

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Detalles Bibliográficos
Autores principales: Yamada, Kohji, Hayashi, Mutsumi, Du, Wenlin, Ohnuma, Kei, Sakamoto, Michiie, Morimoto, Chikao, Yamada, Taketo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709605/
https://www.ncbi.nlm.nih.gov/pubmed/19555512
http://dx.doi.org/10.1186/1475-2867-9-17