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Antimicrobial breakpoint estimation accounting for variability in pharmacokinetics

BACKGROUND: Pharmacokinetic and pharmacodynamic (PK/PD) indices are increasingly being used in the microbiological field to assess the efficacy of a dosing regimen. In contrast to methods using MIC, PK/PD-based methods reflect in vivo conditions and are more predictive of efficacy. Unfortunately, th...

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Detalles Bibliográficos
Autores principales: Bi, Goue Denis Gohore, Li, Jun, Nekka, Fahima
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709609/
https://www.ncbi.nlm.nih.gov/pubmed/19558679
http://dx.doi.org/10.1186/1742-4682-6-10