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Antimicrobial breakpoint estimation accounting for variability in pharmacokinetics
BACKGROUND: Pharmacokinetic and pharmacodynamic (PK/PD) indices are increasingly being used in the microbiological field to assess the efficacy of a dosing regimen. In contrast to methods using MIC, PK/PD-based methods reflect in vivo conditions and are more predictive of efficacy. Unfortunately, th...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709609/ https://www.ncbi.nlm.nih.gov/pubmed/19558679 http://dx.doi.org/10.1186/1742-4682-6-10 |