Structure-activity relationship analysis of cytotoxic cyanoguanidines: selection of CHS 828 as candidate drug

BACKGROUND: N-(6-(4-chlorophenoxy)hexyl)-N'-cyano-N''-4-pyridyl guanidine) (CHS 828) is the first candidate drug from a novel group of anti-tumour agents – the pyridyl cyanoguanidines, shown to be potent compounds interfering with cellular metabolism (inhibition of nicotinamide phosph...

Descripción completa

Detalles Bibliográficos
Autores principales: Lövborg, Henrik, Burman, Robert, Gullbo, Joachim
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709656/
https://www.ncbi.nlm.nih.gov/pubmed/19563661
http://dx.doi.org/10.1186/1756-0500-2-114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709656/
https://www.ncbi.nlm.nih.gov/pubmed/19563661
http://dx.doi.org/10.1186/1756-0500-2-114

Ejemplares similares