Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

Mutations in the gene encoding the microtubule (MT)-severing protein spastin are the most common cause of hereditary spastic paraplegia, a genetic condition in which axons of the corticospinal tracts degenerate. We show that not only does endogenous spastin colocalize with MTs, but that it is also l...

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Detalles Bibliográficos
Autores principales: Connell, James W, Lindon, Catherine, Luzio, J Paul, Reid, Evan
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709849/
https://www.ncbi.nlm.nih.gov/pubmed/19000169
http://dx.doi.org/10.1111/j.1600-0854.2008.00847.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709849/
https://www.ncbi.nlm.nih.gov/pubmed/19000169
http://dx.doi.org/10.1111/j.1600-0854.2008.00847.x

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