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Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion
Mutations in the gene encoding the microtubule (MT)-severing protein spastin are the most common cause of hereditary spastic paraplegia, a genetic condition in which axons of the corticospinal tracts degenerate. We show that not only does endogenous spastin colocalize with MTs, but that it is also l...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709849/ https://www.ncbi.nlm.nih.gov/pubmed/19000169 http://dx.doi.org/10.1111/j.1600-0854.2008.00847.x |