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Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response

AIMS/HYPOTHESIS: We investigated whether variation in MTNR1B, which was recently identified as a common genetic determinant of fasting glucose levels in healthy, diabetes-free individuals, is associated with measures of beta cell function and whole-body insulin sensitivity. METHODS: We studied 1,276...

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Detalles Bibliográficos
Autores principales: Langenberg, C., Pascoe, L., Mari, A., Tura, A., Laakso, M., Frayling, T. M., Barroso, I., Loos, R. J. F., Wareham, N. J., Walker, M.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709880/
https://www.ncbi.nlm.nih.gov/pubmed/19455304
http://dx.doi.org/10.1007/s00125-009-1392-x