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The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons

Some of the tryptophan catabolites produced through the kynurenine pathway (KP), and more particularly the excitotoxin quinolinic acid (QA), are likely to play a role in the pathogenesis of Alzheimer's disease (AD). We have previously shown that the KP is over activated in AD brain and that QA...

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Detalles Bibliográficos
Autores principales: Rahman, Abdur, Ting, Kaka, Cullen, Karen M., Braidy, Nady, Brew, Bruce J., Guillemin, Gilles J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709912/
https://www.ncbi.nlm.nih.gov/pubmed/19623258
http://dx.doi.org/10.1371/journal.pone.0006344