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The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons
Some of the tryptophan catabolites produced through the kynurenine pathway (KP), and more particularly the excitotoxin quinolinic acid (QA), are likely to play a role in the pathogenesis of Alzheimer's disease (AD). We have previously shown that the KP is over activated in AD brain and that QA...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709912/ https://www.ncbi.nlm.nih.gov/pubmed/19623258 http://dx.doi.org/10.1371/journal.pone.0006344 |