Hypocretin-2 Saporin Lesions of the Ventrolateral Periaquaductal Gray (vlPAG) Increase REM Sleep in Hypocretin Knockout Mice

Ten years ago the sleep disorder narcolepsy was linked to the neuropeptide hypocretin (HCRT), also known as orexin. This disorder is characterized by excessive day time sleepiness, inappropriate triggering of rapid-eye movement (REM) sleep and cataplexy, which is a sudden loss of muscle tone during...

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Detalles Bibliográficos
Autores principales: Kaur, Satvinder, Thankachan, Stephen, Begum, Suraiya, Liu, Meng, Blanco-Centurion, Carlos, Shiromani, Priyattam J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709920/
https://www.ncbi.nlm.nih.gov/pubmed/19623260
http://dx.doi.org/10.1371/journal.pone.0006346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709920/
https://www.ncbi.nlm.nih.gov/pubmed/19623260
http://dx.doi.org/10.1371/journal.pone.0006346

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