Combining specificity determining and conserved residues improves functional site prediction

BACKGROUND: Predicting the location of functionally important sites from protein sequence and/or structure is a long-standing problem in computational biology. Most current approaches make use of sequence conservation, assuming that amino acid residues conserved within a protein family are most like...

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Detalles Bibliográficos
Autores principales: Kalinina, Olga V, Gelfand, Mikhail S, Russell, Robert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709924/
https://www.ncbi.nlm.nih.gov/pubmed/19508719
http://dx.doi.org/10.1186/1471-2105-10-174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709924/
https://www.ncbi.nlm.nih.gov/pubmed/19508719
http://dx.doi.org/10.1186/1471-2105-10-174

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