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Combining specificity determining and conserved residues improves functional site prediction
BACKGROUND: Predicting the location of functionally important sites from protein sequence and/or structure is a long-standing problem in computational biology. Most current approaches make use of sequence conservation, assuming that amino acid residues conserved within a protein family are most like...
Autores principales: | Kalinina, Olga V, Gelfand, Mikhail S, Russell, Robert B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709924/ https://www.ncbi.nlm.nih.gov/pubmed/19508719 http://dx.doi.org/10.1186/1471-2105-10-174 |
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