Cargando…

Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization

[Image: see text] Chemical inducers of dimerization (CIDs) are cell-permeable small molecules capable of dimerizing two protein targets. The most widely used CID, the natural product rapamycin and its relatives, is immunosuppressive due to interactions with endogenous targets and thus has limited ut...

Descripción completa

Detalles Bibliográficos
Autores principales: Czlapinski, Jennifer L., Schelle, Michael W., Miller, Lawrence W., Laughlin, Scott T., Kohler, Jennifer J., Cornish, Virginia W., Bertozzi, Carolyn R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2008
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2709988/
https://www.ncbi.nlm.nih.gov/pubmed/18788807
http://dx.doi.org/10.1021/ja8037728